Sleep problems may indicate multiple sclerosis risk

Toronto, July 17 : Scientists have found that multiple sclerosis (MS) may be identified at least five years earlier as the patients were more likely to undergo treatments for nervous system disorders like pain or sleep problems, according to a study.

MS results from the body's immune system attacking myelin -- fatty material that enables rapid transmission of electrical signals -- which disrupts the communication between the brain and other parts of the body, leading to vision problems, muscle weakness, difficulty with balance and coordination, and cognitive impairments.

"The existence of such 'warning signs' are well-accepted for Alzheimer's disease and Parkinson's disease, but there has been little investigation into a similar pattern for MS," said lead researcher Helen Tremlett from the Division of Neurology at University of British Columbia in Canada.

"We now need to delve deeper into this phenomenon, perhaps using data-mining techniques. We want to see if there are discernible patterns related to sex, age or the 'type' of MS they eventually develop," Tremlett added.

For the study, published in Multiple Sclerosis Journal, the team examined health records of 14,000 people with multiple sclerosis and compared them to the health records of 67,000 people without the disease.

Fibromyalgia -- a condition involving widespread musculoskeletal pain -- was found more than three times in people who were later diagnosed with MS as compared to those who did not.

Irritable bowel syndrome was almost twice as common in people who developed the disorder. Migraine headaches and any mood or anxiety disorder, which includes depression, anxiety and bipolar disorder were also found in higher rates among the group.

Further, higher rates of these illnesses also corresponds with higher use of medications for musculoskeletal disorders, nervous system disorders, and disorders of the genito-urinary tract, along with antidepressants and antibiotics.

The findings may enable physicians to diagnose the disease earlier and start the treatment, thus possibly slowing the damage it causes to the brain and spinal cord.