Health
Poor sleep increases pain in knee osteoarthritis
Poor sleep increases pain in knee osteoarthritis
New York, June 4 Poor sleep can amplify pain in patients with knee osteoarthritis (OA) - a degenerative joint disease that causes pain and swelling of joints in the hand, hips or knee.
Researchers from Johns Hopkins University School of Medicine in Baltimore, Maryland, found that OA patients who have poor sleep habits displayed greater central sensitisation - an amplification of clinical pain.
Central sensitisation is a condition of the nervous system that is associated with the development and maintenance of chronic pain.
The findings further showed that OA patients who catastrophise - consumed by thoughts of pain - had increased central sensitisation that was associated with greater pain.
"Our study is the largest and most comprehensive examination of the relationship between sleep disturbance, catastrophising and central sensitisation in knee OA," said lead study author Claudia Campbell from the department of psychiatry and behaviuoral sciences.
For the study, the team analysed 208 participants.
Results show that the subjects with knee OA and insomnia had the greatest degree of central sensitisation compared to the controls.
The team found patients with poor sleep and high catastrophising scores reported increased levels of central sensitisation.
In turn, central sensitisation was significantly associated with increased clinical pain.
"Understanding the intricate relationship between sleep, central sensitisation and catastrophizing has important clinical implications for treating those with chronic pain conditions such as knee OA," the authors said.
The study was published in Arthritis Care & Research, a journal of the American College of Rheumatology (ACR).
6 hours ago
The BioInnovation Institute and Science presented the Innovation Prize to Indian American Aditya Kunjapur
6 hours ago
Pennsylvania Republican primary results show Haley with over 150,000 votes.
6 hours ago
Mandates airline refunds and fee transparency introduced by Biden
6 hours ago
Initiative to tackle newborn malnutrition in rural India promoted by the Indian Consulate in NY
7 hours ago
In Los Angeles, a high-ranking US diplomat convenes with the Jain community
7 hours ago
The Peabody Award has nominated two Indian documentaries as finalists.
just now
8 hours ago
Indian rupee to appreciate to Rs 82–82.50 in FY25: CARE Ratings
8 hours ago
Reservation given earlier to Muslim community continued in K’taka: CM Siddaramaiah
8 hours ago
Congress, SP playing divisive politics, says PM Modi in Agra
8 hours ago
Nestle India’s net profit up 27 pc in Q4; to form a JV with Dr Reddy’s Laboratories
8 hours ago
BMW's another all-electric car launched in India
8 hours ago
Cong candidate in Kerala suspects foul play as list of poll officials leaked, one suspended